Holarrhena antidysenterica is used to detoxify the body and relieve tiredness. Suchitra mahato, anita mehta1 and soma roy2 department of biotechnology, ranchi womens college, ranchi 834 008 jharkhand, india 1department of botany, ranchi womens college, ranchi 834 008 jharkhand, india. It is commonly grown throughout in india, ascending to 4,000ft. Also known as kurchi, vatsak, or kutaj, this herb is a favorite among travelers to support digestion and wellformed stools while journeying through faroff lands. Dpph radical scavenging assay dpph radical scavenging activity was measured as per standard method using stable dpph radical7. Its effects on bacterial outer membrane permeability and ef. Holarrhena antidysenterica,dpph, abts, flavonoid, antioxidant, neutraceuticals. Pdf evaluation of antidiarrheal activity of ethanolic. The juice from its bark is used for the relief of mouth sores and its leaves are used for the treatment of several skin disorders, psoriasis and other nonspecific dermatitis. Antiinflammatory and analgesic activities of holarrhena.
Holarrhena antidysenterica kurchikutaj is a drug of choice in amebic dysentery. The bark is used as an adulterant for the well known drug, holarrhena antidysenterica. The unfortunate thing being that people remembered antidysenterica but never bothered to know where it came from, and got tagged wrongly to holarrhena antidydenterica l. Jhandar shah, university of malakand, chakdara, khyber pakhtunkhwa, pakistan and voucher specimen hase010871 was submitted to the herbarium of the department of biological and biomedical sciences, the aga khan university, karachi. Holarrhena antidysenterica holarrhena pubescens kurchi or. Wrightia antidysenterica national botanical research. Flowers are white in color, found in axillary or terminal. The clinical study records the clinical presentations of forty cases with amoebias and or giardiasis including the efficacy of kutaja holarrhena antidysenterica in intestinal amoebiasis. Because of lack of hygienic conditions of living and. Holarrhena antidysenterica plant grows as a deciduous shrub up to 3ms high. It completely kills entamoeba histolytica, the causative agent of. Standardization of formulations containing holarrhena 9antidysentrica standardization of some plantbased formulations by modern analytical techniques 217 9. Holarrhena antidysenterica as a resistance modifying agent against acinetobacter baumannii.
Apocynaceae is widely used in traditional medical system for treatment of constipation, colic, and diarrhea. Dried seeds of holarrhena antidysenterica were taken from local herbal store, identified by a taxonomist, prof. Standardization of some plantbased formulations by modern analytical techniques 229. Its main goal is summarize the most relevant or attractive characteristics of this taxon to the general public. A moderate grower with several short and divaricate branches that turn chocolaty brown as it ages, and adorned with dark green, ovate and acuminate leaves 2. Evidencebased complementary and alternative medicine hindawi. Jan 21, 2016 holarrhena antidysenterica kurchikutaj has bitter astringent taste, but it is beneficial for dysentery and diarrhea. It has long been known in indian ayurvedic tradition. Holarrhena pubescens in the germplasm resources information network grin, u. Plants profile for holarrhena antidysenterica tellicherry. The indications of bark powder of holarrhena antidysenterica wall ex a.
The temperament of holarrhena antidysenterica wall ex a. Faculty of pharmacy rajarshi rananjay sinh college of pharmacy, amethi227405, uttar pradesh, india. The role of ntfps in poverty alleviation and biodiversity conservation i preface nontimber forest products ntfps play an important role in the livelihoods of the rural poor, as a source of food, medicine, construction materials, and income throughout the world. Holarrhena antidysenterica homeopathic medicine history. Wrightia antidysenterica is a small and compact semideciduous shrub, reaching 1. In india, early height increment of holarrhena pubescens is low, only 10 15 cmyear under natural conditions. Apr 22, 2011 a large shrub or small tree grows up to 10 meters in height. Leaves simple, opposite, ovate, acuteacuminate pubescent and membranous.
General information wrightia antidysenterica is a compact, evergreen shrub that can grow up to 1. It is native to central and southern africa, the indian subcontinent, indochina. Explants used for callus induction were shoot segments derived from 14dold axenic plants on murashige and skoog ms medium supplemented with 15. Get a printable copy pdf file of the complete article 2. Standardization of formulations containing holarrhena 9antidysentrica. Wrightia antidysenterica, the coral swirl or tellicherry bark, is a flowering plant in the genus wrightia.
Kutaj holarrhena antidysenterica, kutaja 100 vegicaps. Its uses are mentioned in the classical ayurvedic literature. The leaves are used in treating several skin disorders, psoriasis, nonspecific dermatitis etc. Holarrhena antidysenterica belongs to the family apocynaceae.
Apocynaceae, inflammation, methanolic extract, pain introduction holarrhena antidysenterica wall. Holarrhena antidysenterica synonyms, holarrhena antidysenterica pronunciation, holarrhena antidysenterica translation, english dictionary definition of. No contra indication information is available for holarrhena antidysenterica wall ex a. Pharmacological basis for the medicinal use of holarrhena. Don this is a gallery page containing specially selected images. It is an old indian medicine, known by the common name kurchi. Although holarrhena pubescens has been known as a medicinal plant since historic times, data on its production and international trade are scarce. Free radical scavenging activity of seed of holarrhena.
Studies on the in vitro and in vivo antiurolithic activity of. The methanolic extract of the leaves and seeds of holarrhena antidysenterica showed mild cytotoxic activity against brine shrimp nauplii with respectively lc 50 value of 0. Steroidal alkaloids and conessine from the medicinal plant. Save nature to survive studies on antibacterial effects of. Steroidal alkaloids from holarrhena antidysenterica, and particularly the principal active ingredient conessine, restored levofloxacin efficacy.
As its botanical name antidysenterica implies, kutaja holarrhena antidysenterica is one of the best ayurvedic herbs for bolstering the natural defenses of the gi tract. Pdf holarrhena antidysenterica is a very significant herbal drug in unani system of medicine and ayurvedic system of medicine. Holarrhena antidysenterica as a resistance modifying agent. The bark possesses antimicrobial and antiinfammatory properties and therefore the juice extracted from it is administered for mouth sores. Wrightia antidysenterica is sometimes confused with the species holarrhena pubescens due to a second, taxonomically invalid publication of the name holarrhena pubescens. Files are available under licenses specified on their. This study was carried out to provide pharmacological basis for medicinal use of holarrhena antidysenterica in gastrointestinal disorders. Study of bioactivities of holarrhena pubescence growing in.
In subsequent years, growth is more rapid, the mean annual diameter increment being 7 8 mm. Herbal practices similar to the ones given below may also have been received from other people from same different parts of the country. Specimens from india have in general shorter sepals and more acute to acuminate leaves but there are intermediates making it impossible to separate the african material as a distinct species, and no advantage can be seen in attempting to maintain varieties. Holarrhena pubescens is a species of flowering plant in the family apocynaceae.
Its uses are mentioned in the classical ayurvedic literature and by. Holarrhena pubescens in ananthagiri, ap w2 img 9244. Standardization of formulations containing holarrhena. A large shrub or small tree grows up to 10 meters in height. Holarrhena antidysenterica definition of holarrhena. In ayurveda, it is used for the treatment of amoebic dysentery, diarrhoea, irritable bowel syndrome, bleeding piles, and liver disorders.
The stem bark of holarrhena antidysenterica were ground to a coarse powder and stored at room temperature. Full text is available as a scanned copy of the original print version. Patients suffering liver and kidney problem must avoid the use of this. It reduces mucus content in stool and check bleeding. Holarrhena antidysenterica holarrhena pubescens kurchi. Antidiabetic potential of ethanolic extract of holarrhena. Holarrhena antidysenterica synonyms, holarrhena antidysenterica pronunciation, holarrhena antidysenterica translation, english dictionary definition of holarrhena antidysenterica. The failure of the alkaloids of holarrhena antidysenterica kurchi. Holarrhena antidysenterica medicinal benefits and images.
It is native to central and southern africa, the indian subcontinent, indochina, and parts of china. Pdf pharmacognostic and phytochemical evaluation of. Department of agriculture agricultural research service. Antimalarial and cytotoxic activities of pregnenetype steroidal. Efficient plant regeneration in holarrhena antidysenterica. Effect of the standardized extract of holarrhena antidysenterica seeds against steptozotocininduced diabetes in rats vinay kumar pathak1, anup maiti1, shyam sundar gupta2, ila shukla2, ch. The present study was conducted to evaluate the antidiarrheal effect of ethanolic extract of holarrhena antidysenterica family apocynaceae seeds against induced diarrhea in wistar albino. Apocynaceae, distributed throughout sri lanka and india, has been used as a folk remedy to treat various diseases.
The flowers have five white petals and grow up to 23cm high. The doubling time and specific growth rate of cells in suspension culture were computed to be 47. Callus and suspension culture of holarrhena antidysenterica were established for production of steroidal alkaloids, especially conessine. Buy kutaja online organic kutaja powder for sale banyan.
The traditional knowledge examples given below are just an indicativeillustrative sample. Holarrhena antidysenterica possesses some side effects such as sleeplessness. Due to the resistance presence of steroid alkaloids, this plant possesses antibacterial. A procedure has been outlined for plant regeneration of an important medicinal shrub, holarrhena antidysenterica, through shoot segmentderived callus. International journal of pharma sciences and research ijpsr. Apr 23, 2016 plant holarrhena antidysenterica medicinal benefits. This study aimed to evaluate the efficacy of combinations of steroidal alkaloids and conessine from the thai medicinal plant holarrhena antidysenterica with antibiotics against pseudomonas aeruginosa strains possessing different effluxpumpmediated multidrugresistant mdr phenotypes in a galleria mellonella infection model.